Дева писал(а):Хвост
третий генотип (((( я бы не была столь уверенна в советах. У вас то первый.
По последним наблюдениям, я выше писала уже даже с ф0 от 16 нелель тера при 3 гене и риб лишним не будет.
Ниже рекомендации AASL 2016 года.
Заметьте, Соф+Дак+Риб даже на третьем генотипе рекомендуются только при церозе.......и ...... на 24 недели!
А если уж без цироза, то будьте добры Соф+Риб+....Пегасис
Говорят же нам постоянно врачи - "Не занимайтесь самолечением!!!" ( это я только по отношению к рибаверину :)
Думаю не дураки в AASL сидят:
Genotype 3 Treatment-naïve Patients without Cirrhosis - Recommended
Recommended regimens are listed in groups by level of evidence, then alphabetically.
> Daily daclatasvir (60 mg*) plus sofosbuvir (400 mg) for 12 weeks is a Recommended
regimen for treatment-naïve patients with HCV genotype 3 infection who do not have
cirrhosis.
Rating: Class I, Level A
> Daily sofosbuvir (400 mg) and weight-based RBV plus weekly PEG-IFN for 12 weeks is a
Recommended regimen for treatment-naïve patients with HCV genotype 3 infection who do
not have cirrhosis and who are eligible to receive PEG-IFN.
Rating: Class I, Level A
* The dose of daclatasvir may need to increase or decrease when used concomitantly with
cytochrome P450 3A/4 inducers and inhibitors, respectively. Please refer to the prescribing
information and the section on HIV/HCV coinfection [15] for patients on antiretoviral therapy.
Genotype 3 Treatment-naïve Patients with Compensated Cirrhosis [6]‡-
Recommended
Recommended regimens are listed in groups by level of evidence, then alphabetically.
> Daily sofosbuvir (400 mg) and weight-based RBV plus weekly PEG-IFN for 12 weeks is a
Recommended regimen for treatment-naïve patients with HCV genotype 3 infection who
have compensated cirrhosis [6] and who are eligible to receive PEG-IFN.
Rating: Class I, Level A
> Daily daclatasvir (60 mg*) plus sofosbuvir (400 mg) for 24 weeks with or without weightbased
RBV is a Recommended regimen for treatment-naïve patients with HCV genotype 3
infection who have compensated cirrhosis [6].
Rating: Class IIa, Level B